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Molecular Cell Biology
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Molecular Cell Biology presents the key concepts in cell biology and their experimental underpinnings. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology and health and human disease. As always, a hallmark of MCB is the use of experiments to engage students in the history of cell biology and the research that has contributed to the field.See what's in the LaunchPad
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Product details
Hardcover: 1248 pages
Publisher: W. H. Freeman; 7th edition (May 2, 2012)
Language: English
ISBN-10: 142923413X
ISBN-13: 978-1429234139
Product Dimensions:
8.9 x 1.8 x 11.1 inches
Shipping Weight: 5.4 pounds
Average Customer Review:
4.4 out of 5 stars
140 customer reviews
Amazon Best Sellers Rank:
#164,078 in Books (See Top 100 in Books)
Although I don't claim to be a molecular biologist, nor have I read beyond chapter 5 of Lodish's "Molecular and Cell Biology", this textbook feels admirably thorough in its treatment of its subject, bringing the reader up to date on a wide range of the detail generated in the field over the past few decades.The book's authors, furthermore, have addressed the learning needs of their readership; once it moves into its substantive chapters, virtually all points are made simultaneously with textbook prose and colorful, graphic illustrations which are well drawn and accompanied by excellent captions. This aspect of the book is its great strength.There is a far more serious problem with the book, however, which explains the middling rating I have given it. Like many such textbooks, it is committee-written, which is not a problem when such books are given proper shape by a sharp editor. But the book lacks that editor and as a result dwells on the most trivial developments in its field with exactly the same weight as its bedrock components to a fault. In aiming to be comprehensive, it drowns the reader in a sea of obnoxious detail that begs the book and its authors not to be taken seriously. The book may have been conceived as a reference, but I fear that it will always be assigned chapter rather than passage at a time, as is customary in graduate school courses.The corollary to this situation is that the first several chapters of the book describe a host of laboratory processes, each in enormous detail and overall in serial fashion, without adequately describing the use and purpose for each. The book then explains that each process will be taken up in a later chapter in conjunction with an exploration of the field in which it is mainly used. This is all fine, but does the reader really need to be held accountable for a description of these processes twice, particularly when they are presented so haphazardly initially? At least in the first five chapters, rote memorization is the only learning strategy possible for the vast majority of the material. And while there is nothing wrong with rote memorization, the unconnectedness of the material, combined with its sprawling volume, make these initial chapters virtually useless as learning tools.I recommend this book, therefore, with a strict reservation: it should only be used by a teacher so familiar with it that he can assign "primary", "secondary", and perhaps even "tertiary" passages from it at a time, in order to help the reader build an understanding of molecular biology systematically and rationally structure his study time.
I am a postdoctoral researcher and bought this as a reference. If you don't need this, don't waste your money. Bruce Albert's 'Molecular Biology of the Cell' is 5x better and not 5x the price.
I used this book as the text for a UC Santa Cruz extension course in molecular cell biology. I read about 2/3 of it for course reading assignments and I found it to be excellent. It's clearly and well written but is definitely information dense. You really have to focus closely while you're reading it. Expect to need to read most sections at least twice to absorb the material.The diagrams are plentiful, are well drawn and must also be studied carefully since they contain information not included in the body of the text itself.Information has obviously been updated as new versions of the book have appeared. This 4th edition has many references to publications as recent as 1999.The animations in the accompanying CD are sometimes useful. A good example is the animation in chapter 22 of cell-cell adhesion in leukocyte extravasation.
The authors did a good job correctly pulling together modern information. The information is accurate and drawn from literature. Unlike some textbooks I have used recently, they were no factual errors. The illustrations are good. But, this book fell short on editing. The chapters are not very well organized; information that should be together is scattered throughout a chapter. Also, the language used is unnecessarily difficult at times. Finally, the paragraph organization is poor so you have to read and re-read to get the main points.I would have liked to see better organization and editing. Overall, it is good info but very hard to read and extract what you came for.But I would buy it again.
I just repurchased this 4th edition after realizing that the later editions of Molecular Cell Biology have damped down on biophysical and biochemical aspects of cell biology; much of the equations have been removed from this classic textbook in the later editions. It is a common problem across most biochemistry and cell-biology texts these days - it only serves to dumb-down the current generation of graduate students.
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